When science meets medical passion, dreams turn into healthy babies. Science, Hope, and Results Endometriosis doesn't just cause physical pain—it creates invisible walls between couples and their dream of becoming parents. At EndoGlobal Group, we break down those walls by combining two powerful technologies: IVF and PGT. In this article, you'll learn how these techniques …
When science meets medical passion, dreams turn into healthy babies.
Science, Hope, and Results
Endometriosis doesn’t just cause physical pain—it creates invisible walls between couples and their dream of becoming parents. At EndoGlobal Group, we break down those walls by combining two powerful technologies: IVF and PGT. In this article, you’ll learn how these techniques enhance your chances of a healthy pregnancy, why we’re leaders in reproductive genetics in northwestern Mexico, and how we turn scientific complexity into real-life results.
Key phrase: Investing in a genetically healthy embryo today eliminates uncertainty tomorrow.
Understanding the Challenge: Endometriosis and Fertility
Affecting nearly 10% of reproductive-age women, endometriosis occurs when tissue similar to the uterine lining grows outside the uterus, triggering chronic pelvic inflammation and impairing endometrial receptivity. These factors significantly reduce natural fertility.
At EndoGlobal Group, we unite experts in minimally invasive surgery, reproductive endocrinology, and genetics to tackle this condition at its core. After managing inflammation through advanced laparoscopic techniques or medical therapy, we proceed with high-precision assisted reproduction.
Patients with endometriosis who undergo conservative surgery followed by IVF + PGT show a cumulative live birth rate of 72% per cycle—nearly double the 38% achieved with standard IVF alone.
What Is In Vitro Fertilization (IVF)?
IVF involves retrieving mature eggs from the ovaries, fertilizing them with sperm in a controlled laboratory setting, and transferring the resulting embryos into the uterus. IVF provides several critical benefits for endometriosis patients:
- It avoids the inflammatory pelvic environment.
- It allows for the selection of embryos based on morphology.
- It enables optimal timing with a receptive endometrium.
At EndoGlobal Group, we use advanced time-lapse incubators that track each embryo’s development in real time. These micro-observations help us select the embryo with the highest implantation potential.
Convincing phrase: Every embryo we observe through the time-lapse lens tells us a story—our mission is to choose the perfect protagonist for your family.
What Is Preimplantation Genetic Testing (PGT)?
PGT is a technique that analyzes embryos before they are transferred, ensuring the selection of genetically healthy ones. There are three main types:
- PGT-A screens for abnormal chromosome numbers.
- PGT-M identifies single-gene disorders like cystic fibrosis.
- PGT-SR detects structural chromosomal rearrangements that could affect embryo viability.
The testing process involves extracting 5–8 cells from the embryo’s trophectoderm (the part that becomes the placenta) on day 5 or 6 of development, then analyzing the DNA using next-generation sequencing (NGS).
The benefits are clear:
- Up to 70% lower miscarriage risk.
- Fewer transfers needed.
- Greater emotional security through early clarity.
Impactful phrase: PGT is not just a test—it’s a filter of peace that turns probabilities into certainties.
The Synergy of IVF + PGT in Endometriosis
Endometriosis-related inflammation can compromise egg quality and embryo implantation. By fertilizing eggs outside the body and selecting genetically normal embryos, we eliminate two major hurdles.
We also employ a frozen embryo transfer strategy, ensuring embryos are placed only when the uterus is perfectly prepared. Our single-euploid embryo transfer approach reduces the risk of multiples while maintaining high success rates.
EndoGlobal Group data:
- Implantation rate with standard IVF: 35%
- Implantation rate with IVF + PGT: 58%
Powerful phrase: When we combine genetic selection with a receptive uterus, endometriosis no longer dictates the rules.
The EndoGlobal Group Process
Our process begins with a thorough evaluation, including 3D ultrasound, inflammatory markers, and a personalized nutrition and emotional wellness plan.
If needed, we perform advanced laparoscopic surgery to map and remove deep endometriosis lesions. We then move to mild ovarian stimulation protocols tailored to each patient, followed by egg retrieval and intracytoplasmic sperm injection (ICSI) when male factor infertility is present.
Embryos are cultured in time-lapse incubators and undergo trophectoderm biopsy for PGT. Euploid embryos are vitrified for later transfer.
We prepare the endometrium with a customized hormonal plan, ensuring a trilaminar pattern and adequate thickness, then transfer the embryo using an ultra-soft catheter under ultrasound guidance.
Post-transfer, we offer comprehensive support with progesterone supplementation, emotional guidance, and nutritional monitoring.
Motivational phrase: From the first consultation to your positive pregnancy test, we walk beside you—step by step, heartbeat by heartbeat.
Scientific Evidence and Success Rates
According to the American Society for Reproductive Medicine (ASRM), PGT-A increases live birth rates from 42% to 55% in women under 38. In endometriosis patients, success is even higher due to the exclusion of genetically compromised embryos.
EndoGlobal Group outcomes (2023–2025):
- 286 IVF + PGT cycles in endometriosis patients
- Clinical pregnancy rate: 67%
- Miscarriage rate: 7% (vs. 18% without PGT)
- Live birth rate per transfer: 60%
Compelling quote: Statistics don’t lie—behind every percentage point are complete families.
Dispelling Misconceptions
There are lingering myths around embryo biopsy and IVF. Some believe the biopsy harms development, but modern techniques maintain over 95% viability. Others think PGT is only useful for older women, but it benefits patients of all ages by minimizing genetic risk. And the idea that IVF always leads to twins is outdated—our single embryo transfer policy results in multiple pregnancies in less than 2% of cases.
Reassuring phrase: Knowledge replaces fear—and fear-free spaces make room for hope.
Extended FAQs
How many embryos are needed for PGT?
We recommend 5–6 blastocysts. In severe endometriosis, we optimize every retrieved egg to reach this goal.
Does PGT replace prenatal screening?
No. We still advise non-invasive prenatal testing (NIPT) and detailed ultrasounds.
Are financing options available?
Yes. We offer flexible payment plans and partner with medical financing institutions.
Can I attempt a second pregnancy with frozen embryos?
Yes. You can plan your next transfer without undergoing ovarian stimulation again.
Is surgery always necessary before IVF in endometriosis?
Not always. However, deep pelvic lesions that distort anatomy may benefit significantly from surgical removal.
Your Future Begins Now
Endometriosis no longer needs to stand between you and parenthood. The combination of IVF + PGT offers a precise, personalized approach to overcoming reproductive challenges. At EndoGlobal Group, you’ll find everything you need under one roof—minimally invasive surgery, cutting-edge laboratory technology, and world-class reproductive genetics.
Final phrase: The perfect moment to believe in science—and in your dreams—is now.
Article by Dr. Fabián Walters Arballo, Specialist in Reproductive Endocrinology, EndoGlobal Group
Disclaimer: This content is for educational purposes only and does not replace personalized medical consultation.
