Understanding Endometriomas: Do They Have to be Removed?

Endometriomas, often referred to as “chocolate cysts,” are a common manifestation of endometriosis – a medical condition that affects an estimated 200 million women globally. When endometriosis occurs in the ovaries, it can form a fluid-filled sac known as an endometrioma. The cysts, characterized by their dark, chocolate-like fluid, are a serious concern due to their potential impact on a woman’s reproductive health…

The question of whether endometriomas need to be removed is complex. It depends on a range of factors from the size and symptoms of the cysts, to the patient’s age and fertility goals. This article aims to explore the intricacies of endometriomas and provide an in-depth understanding of the condition.

1. What are Endometriomas?

Endometriomas are cysts of endometriosis tissue that form anywhere in the body, being the ovaries one of the most common sites. They are filled with dark, old menstrual blood, which gives them a characteristic chocolate-like appearance.

1.1 Prevalence of Endometriomas

Endometriomas are a relatively common manifestation of endometriosis, detected via ultrasound in approximately 15-40% of women with symptoms suggestive of endometriosis.

1.2 Symptoms of Endometriomas

While some women with endometriomas may not experience any symptoms, others may suffer from severe pelvic pain, painful periods, and painful intercourse. Endometriomas can also contribute to infertility and decrease ovarian function.

Approximately 30 to 50% of infertile women have endometriosis. Endometriomas can affect fertility in several ways. They can cause scarring and adhesions, which can distort the physical anatomy and make ovulation and fertilization difficult.

2.1 Impact on Ovarian Reserve

Women with endometriomas often have fewer eggs in the ovarian tissue surrounding the endometrioma, impaired egg maturation, and a higher follicle-stimulating hormone (FSH) level.

2.2 In Vitro Fertilization (IVF) and Endometriomas

When it comes to IVF, women with endometriomas may experience a decreased response to gonadotropins, leading to a higher IVF cycle cancellation rate.

3. Do Endometriomas Need to be Removed?

The decision to remove endometriomas is not straightforward. The optimal treatment should take into account individual patient factors, including the type and severity of symptoms, age, fertility, and treatment goals.

3.1 Expectant Management

For small, asymptomatic endometriomas with a benign ultrasound appearance, expectant management may be an option.

3.2 Medical Management

Various medical therapies, such as nonsteroidal anti-inflammatory drugs (NSAIDs), oral contraceptives, and progestins, can help alleviate pain associated with endometriosis and endometriomas. However, they cannot eliminate cyst formation and the endometrioma may continue to grow once the medical treatment is discontinued.

3.3 Surgical Management

Surgical removal of endometriomas may be appropriate in certain cases, such as when the endometrioma is large (≥4 cm), causing severe pain, or when malignancy cannot be excluded.

3.3.1 Risks of Surgical Management

However, surgical intervention for endometriomas can also pose risks. It can lead to a significant decline in the anti-Müllerian hormone (AMH), indicating a reduced ovarian reserve. There’s also a risk of damaging the ovarian cortex during cyst removal.

3.3.2 Techniques for Surgical Management

The technique used for the surgical removal of endometriomas is critical. The goal is to remove the entire endometrioma without disturbing the ovarian tissue underneath. This requires a high level of surgical expertise and a meticulous approach.

4. Managing Fertility Concerns with Endometriomas

The decision between surgical removal of endometriomas and fertility preservation is a delicate balance.

4.1 Surgical Removal vs. IVF

While surgical removal of endometriomas can alleviate pain and reduce the risk of malignancy, it can also impact ovarian reserve and potentially disrupt fertility. On the other hand, IVF may help achieve pregnancy, even with the presence of endometriomas.

4.2 Egg Freezing

For women with endometriosis and endometriomas who are concerned about preserving their fertility, egg freezing may be an option. This can provide a potential future opportunity for pregnancy, even after the removal of endometriomas or other impacts of endometriosis on fertility.

5. Patient Advocacy and Empowerment

Understanding endometriomas and their potential impact on fertility and overall health is crucial for women with endometriosis. Being informed and advocating for personalized care can lead to better outcomes.